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Statins Do Not Decrease Small, Dense Low-Density Lipoprotein

Cheol Ung Choi, MD, Hong Seog Seo, MD, […], and Dong Joo Oh, MD

Statins are proven to be detrimental in many ways to our health yet the drug manufacturers continue to push the narrative that they are not only safe but virtually everyone should be on one.

STATIN DRUGS ARE HARMFUL: REFERENCES

References: This “Miracle Drug” Destroys Your heart

Sattar N, Preiss D, Murray HM, et al. Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials. Lancet. 2010 Feb 27;375(9716):735-42. Epub 2010 Feb 16.

Tierney EF, Thurman DJ, Beckles GL, Cadwell BL. The association of statin use with peripheral neuropathy in the US population 40 years of age or older. J Diabetes. 2012 Nov 1. [Epub ahead of print]

FDA Drug Safety Communication: Important safety label changes to cholesterol-lowering statin drugs. FDA. Feb 2012.

Machan CM, Hrynchak PK, Irving EL. Age-related cataract is associated with type 2 diabetes and statin use. Optom Vis Sci. 2012 Aug;89(8):1165-71.

Nakazato R, Gransar H, Berman DS, Cheng VY, et al. Statins use and coronary artery plaque composition: results from the International Multicenter CONFIRM Registry. Atherosclerosis. 2012 Nov;225(1):148-53. Epub 2012 Aug 24.

Taylor F, Huffman MD, Macedo AF, Moore THM, Burke M, Davey Smith G, Ward K, Ebrahim S. Statins for the primary prevention of cardiovascular disease. Cochrane Database of Systematic Reviews 2013, Issue 1

Rubinstein J, Aloka F, Abela GS. Statin therapy decreases myocardial function as evaluated via strain imaging. Clin Cardiol. 2009 Dec;32(12):684-9.

University of Copenhagen (2013, January 3). Cholesterol medicine affects energy production in muscles. ScienceDaily. Retrieved March 18, 2013, from http://www.sciencedaily.com¬ /releases/2013/01/130103114211.htm

Universitat de Barcelona (2013, February 25). Mediterranean diet helps cut risk of heart attack, stroke: Results of PREDIMED study presented. ScienceDaily. Retrieved February 28, 2013, from http://www.sciencedaily.com¬

Gouni-Berthold I, Berthold HK. Policosanol: clinical pharmacology and therapeutic significance of a new lipid-lowering agent. Am Heart J. 2002 Feb;143(2):356-65

References: Statins: The Biggest Fraud

FDA Drug Safety Communication: Important safety label changes to cholesterol-lowering statin drugs. FDA. Feb 2012.

Sukhija R, et al. Effect of statins on fasting plasma glucose in diabetic and nondiabetic patients. J Investig Med. 2009 Mar;57(3):495-9.

Nakazato R, et al. Statins use and coronary artery plaque composition: results from the International Multicenter CONFIRM Registry. Atherosclerosis. 2012 Nov;225(1):148-53.

Saremi A, et al. Progression of vascular calcification is increased with statin use in the Veterans Affairs Diabetes Trial (VADT). Diabetes Care. 2012 Nov;35(11):2390-2.

Sultan S, et al. The Ugly Side of Statins. Systemic Appraisal of the Contemporary Un-Known Unknowns. Open Journal of Endocrine and Metabolic Diseases. 2013, 3, 179-185

Choi CU, et al. Statins Do Not Decrease Small, Dense Low-Density Lipoprotein. Tex Heart Inst J. 2010; 37(4): 421–428.

Morgan JM, et al. Effects of extended-release niacin on lipoprotein subclass distribution. Am J Cardiol. 2003 Jun 15;91(12):1432-6.

Kapil V, et al. Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: a randomized, phase 2, double-blind, placebo-controlled study. Hypertension. 2015 Feb;65(2):320-7

Sources:Solving The Cholesterol Hoax

Diamond DM, et al. How statistical deception created the appearance that statins are safe and effective in primary and secondary prevention of cardiovascular disease. Expert Rev Clin Pharmacol. 2015 Mar;8(2):201-10.

Frank JW, et al. Will lowering population levels of serum cholesterol affect total mortality? Expectations from the Honolulu Heart Program. J Clin Epidemiol. 1992; 45:333-346.

Mauger JF, et al. Effect of different forms of dietary hydrogenated fats on LDL particle size. Am J Clin Nutr 2003;78:370-5.

Williams P.T. et al. Low-fat diets, lipoprotein subclasses, and heart disease risk.. Am J Clin Nutr December 1999 vol. 70 no. 6 949-950

Siri PW, et al. Influence of dietary carbohydrate and fat on LDL and HDL particle distributions. Curr Atheroscler Rep. 2005 Nov;7(6):455-9.

Moreno JA, et al. The effect of dietary fat on LDL size is influenced by apolipoprotein E genotype in healthy subjects. J Nutr. 2004 Oct;134(10):2517-22.

John M. Morgan, M.D. et al. Effects of extended-release niacin on lipoprotein subclass distribution. American Journal of Cardiology. June 2003; Volume 91, Issue 12 , Pages 1432-1436, 15

Woodman RJ, et al. Docosahexaenoic acid but not eicosapentaenoic acid increases LDL particle size in treated hypertensive type 2 diabetic patients. Diabetes Care. 2003 Jan;26(1):253

References: Does Cholesterol Really Matter

Ahmed MH. What does the future hold for niacin as a treatment for hyperlipidaemia and cardiovascular disease? Journal of Cardiovascular Medicine (Hagerstown). 2010 Aug 3. [Epub ahead of print]

de Lorgeril M. Mediterranean diet, traditional risk factors, and the rate of cardiovascular complications after myocardial infarction: final report of the Lyon Diet Heart Study. Circulation. 1999;99:779-785.

Post Author: teamBHRT_admin

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